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Background: Employee performance in an organization is influenced by several factors such as: work motivation, job satisfaction and transformational leadership style, if all of them are fulfilled properly then the performance of employees will increase. The purpose of this study was to analyze the effect of work motivation, job satisfaction and transformational leadership style on employee performance in Class D Hospital.

Research Methods: This research method uses a quantitative approach with a causal design based on cross-sectional time dimensions. The population in this study used 60 employees as a saturated sample. The data collection technique is in the form of a questionnaire with a measurement scale using a Likert scale. Analysis of the data in this study using multiple regression analysis.

Result: It is known that the coefficient of determination or R Square is 0.774 or equal to 77.4%. This figure means that the variables of work motivation (X1), job satisfaction (X2) and transformational leadership style (X3) affect the performance of employees in class D Hospital by 77.4%.

Implications: Work motivation, job satisfaction and transformational leadership style have a positive effect on employee performance.

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